Let’s talk about this…(especially if you have Diminished Ovarian Reserve, are over 40 or looking into donor eggs).
Now, I’m one to believe that every, single IVF cycle needs to be individualized. We are all different so how can one or even two protocols work for everyone?? I know that many clinics(especially very busy ones) have set protocols that they literally use on EVERYONE. Whether you are 25, 35 or 45, they will put you on the same protocol. Wha…what?? It’s like throwing a dart at a board and hoping it sticks. For me, and my money and health and SANITY…that is not enough. Sure, it may work…but why not give it your best shot on the FIRST try? Not start after you’ve had 3 failed IVF cycles.
So…here we go. I’m going to start a series of posts that does just that…this being the first one: HIER-Highly Individualized Egg Retrievals. This is for my friends who have Diminished Ovarian Reserve(DOR) or Premature Ovarian Failure(POF)…( Low AMH, High FSH, low antral follicle count) or if you are over 40.
HIER is a Highly Individualized Egg Retrieval. Currently, many Reproductive Endocrinologists(RE’s) wait until the lead follicle grows to 18-22mm to trigger the eggs to finish developing accordingly. In a lot of patients, this works. BUT, in certain patients(DOR/POF or over 40), waiting that long is too long. This is what happens in those patients. Premature luteinization of follicles. In practical terms this means that, as women get older, the biological processes within follicles speed up. As a consequence, if the timing of egg retrieval in older women(or those with DOR/POF) is maintained like in younger women, the eggs one obtains are “hard-boiled” rather than “soft-boiled,” or in medical lingo atretic rather than mature and, therefore, unusable.
Basically, what this study found. Early retrieval(triggering when the lead follicle is between 16-18mm(instead of standard retrieval waiting until 18-22mm). If you don’t want to read through the entire study, women over age 43(wow), using a standard retrieval had a 6.7% pregnancy rate, whereas women over 43, using the early retrieval(16-18mm) had a 16.7% pregnancy rate. Almost tripled. And those that were not over 43, but had DOR/POF, had even better pregnancy rates with early retrieval vs standard retrieval. Early retrieval pregnancy rate was 41.7% vs. 7.7% with standard retrieval……wow. Just wow.
A simple tweak in protocol. Triggering just a little bit early. What if triggering early works? What if you didn’t have to use donor eggs after all? Just something to think about…….
Don’t be embarrassed to ask questions….ask your RE…talk about it…research it…
Be an advocate for yourself…..now….
I’m always here for you…..if you have ANY questions, feel free to comment below or send me an email or message through IG!