Category: First IVF Shots

FET #4: Screw Estrogen

O.k….so after having a short 23 day cycle last month….I began FET#4…

So far I’ve been through 3 other FET’s to try to build my lining to an appropriate thickness to carry a pregnancy….it’s only ever gotten to 4mm……every….single….time….

I’ve used Oral Estradiol Estrace (of doses up to 8mg-10mg a day), Vaginal Estrogen suppositories(3mg a day), Viagra, Trental 400mg, Vitamin E 1000mg, Wobenzyme, acupuncture(for the past 2 yrs), I even went to a Chinese Healer…yes…he was on “Ripley’s Believe It or Not” show as able to heal the “unhealable”…I know…I sound desperate…..

and I am….

I’ve had these 6 blastocysts waiting to be transferred since Jan(and one little morula from my first IVF in Nov)….just sitting there…frozen….waiting for a home…..and I’m really trying to give them one…..

So we are here….

2 weeks ago, I started Estradiol Valerate(Delestrogen) shots. They use the same needle size as Progesterone shots. They look like GIANTS compared to the tiny IVF med shots…here’s a pic:

CIMG2235

 

But once again….no reason to freak myself out….we TRULY are stronger than we think….and they are not that bad…you just have to make sure you ice that area…and it’s really numb…, pinch your skin pretty tight…and don’t put the needle in too fast…steady and when I’m pinching my skin I poke my finger nail into my skin too…so I can’t really feel the needle or meds….just a little advice 🙂

Lining checks: Not good 🙁 There is still fluid in my lining and it’s only about 3.6mm…..boo…hoo…also, my E2 is at: 4108…too high….so I’ll lower my dosage of Estradiol Valerate and only 2 Estrogen suppositories instead of 3 per day.

So, to me, obviously estrogen does not work on me….too much, too little…I get the same poor results….thin lining.

I’ve realized I have to be my own scientist. I read all of the literature. All of the studies. ALL OF THEM.

Now that I know estrogen is not going to cut it for me…next month we are trying a drug called Tamoxifen to grow my lining.

It works a little differently than estrogen…it binds differently to certain estrogen receptors….and has shown promise for women with chronically thin lining.

Who knows if it will work….but I’ve gotta try right? I’m not giving up on myself yet.

Obviously, my RE continues to suggest a Gestational Carrier for me. He feels that, that is the only way I’m going to be able to have my own child. He believes that my endometrium has been severly damaged due to my appendix rupturing, causing chronic infection and inflammtion throughout my body. He says that looking into a gestational carrier now would be no harm starting the process because it takes a while and he knows that I still want to try to grow my lining…

What he doesn’t know is that I WILL carry my own baby. Period.

I will not give up on myself. I will not stop researching studies and various techniques throughout the world for women with my problem. There HAS to be a solution. Some link. Some medicine. Some sort of indirect association that just needs to be found to put it all together.

I’m not only doing this for myself….I refuse to give up on the hundreds of other women with this problem, Chronically Thin Endometrium. If they don’t have the strength or opportunity to search and test other options before having to turn to a gestational carrier…I will do the work for them. I will fight for them and I will post everything here.

I didn’t go to med school. I’m not a Dr. or an RE….and I never will be. But I am a patient…and I have a problem….and that problem needs a solution. I understand that certain treatments that “should” work are not working….so maybe we should think out of the box? Obviously my case is unique….therefore I need a UNIQUE plan….seems simple right?!

I am very thankful that my RE has agreed to try “experimental” protocols with me(let’s just say I wouldn’t take no for an answer…ha!). Don’t get me wrong, I don’t want to put my life in danger but I also don’t want to give up on something that I feel can be solved, can be figured out…with a little effort….

So, there ya have it. I will continue these Estradiol Valerate shots for the next week (maybe my lining will miraculously perk up??) and then on to Tamoxifen. It is one of those experimental things….it’s currently used for breast cancer patients but this study showed promising results….for us thin lining ladies….

Don’t give up on hope. Whether it be for thin lining, PCOS, poor egg quality, immune issues, overweight, underweight, no ovulation, RPL, etc…..you are not alone. Remember…there’s always someone in your corner….cheering you on..and fighting for you….

Determination…..that’s what it’s about and I’m ready to battle….

Theres-no-force-equal-to-that-of-a-determined-woman

 

 

IVF #2: Stim Days 1-10

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So here we go again 🙂 Here’s the whole update of how this cycle has gone so far:

*Instead of birth control before stimming, this cycle we did Estrogen. I took 1-2mg Estradiol AM and PM 2 weeks before stimming began

January 3-Ultrasound to make sure my ovary is “quiet” No cysts, small follicles. All looks good to start stims in 2 days.

SD=Stim Day

SD 1-January 5-Start 450IU Gonal-F & 150IU Menopur only in PM

SD 2-January 6– 450IU Gonal-F & 150 IU Menopur only in PM

SD3-January 7– Acupuncture in the afternoon. 300IU Gonal-F & 150IU Menopur only in PM

SD4-January 8– 300 UI Gonal-F & 150 IU Menopur only in PM

SD5-January 9– AM Bloodwork-results E2=362(better than last time was only 69) 300IU Gonal-F & 150IU Menopur only in PM….start feeling sick tonight though…scratchy throat :(((

SD6-January 10-AM Ultrasound results-between 4-6 follicles growing…12,8,8,6(what I could kind of get for measurements?).  I only have one ovary so that’s good enough for me 🙂 Continue to watch.  300IU Gonal-F & 150IU Menopur only in PM. Feeling more sick…oh no, I think I’ve got a bad cold 🙁 great

SD7-January 11– SICK, SICK, SICK…sore throat, stuffy nose, headache…everything..just perfect to go along with IVF 🙁 Oh well…rest all day and then 300IU Gonal-F & 150IU Menopur only in PM

SD8-January 12– Still sick 🙁 Taking tons of Vitamin C(didn’t ask my RE..oops) maybe it will help? I start Ganirelix(250mc prefilled shot) and Saizen(.5) in the AM and 300IU Gonal-F & 150IU Menopur only in PM, Still sick…stuffy nose, coughing…yuck 🙁

SD9-January 13– Lots of EWCM in AM. Ultrasound: 16,15,11,12,9 Much better than last cycle. Moving faster this time around. Lining was 6.2. My RE still doesn’t like the way it looks, still too thin,  start vaginal estrogen supplements in AM & PM. Acupuncture in afternoon…ask her to help with lining and my sickness…please get me better 🙂 Ganirelix(250mc prefilled shot) and Saizen(.5) in the AM and 300IU Follistim(had to switch to Follistim because I ran out of Gonal-F…RE said it was ok) & 150IU Menopur only in PM

SD10-January 14-EWCM. Ultrasound-17, 16,15,14,12,10 I’ll come back tomorrow to see if we will trigger? Lining back down to 5.1 with some mucus?? Arg! Lining…looking more like we will have to do FET later. So let’s just focus on the eggs :)Ganirelix(250mc prefilled shot) and Saizen(.5) in the AM and 300IU Follistim & 150IU Menopur only in PM, and Estrogen Suppositories AM & PM(a LOT of stuff in me…ahh!) Still sick but better, actually much better after acupuncture yesterday.

Now today. January 15-Ultrasound: 18,18,16,15,13,12(again a guess, because I couldn’t see exactly what they wrote). One more day/night of stims..they want some other eggs to catch up..so I’ll go back tomorrow for final ultrasound and we will prob trigger with Ovidrel tomorrow night 🙂 Saturday retrieval!

If you all could please keep me in your prayers..thank you…..just want a couple of perfectly cooked eggs(that will become healthy embryos..and babies 🙂