Category: Estrogen

ERA Test (Endometrial Receptivity Array)-Hope For Thin Lining??

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Sometimes, on days like this, I’m consumed with “figuring out” why my lining refuses to grow.

So, of course, I turn to Dr. Google. But you know what the saddest part about that is? Researching the SAME topic for almost 4 years yields the same results you’ve seen for almost 4 years. Never really anything new. So I re-read articles that I’ve read many times before…and sometimes, you find something you may have missed…some inspiration.

One of the articles, or research papers I’m talking about is this one:

http://www.researchgate.net/publication/260994775_Live_birth_after_embryo_transfer_in_an_unresponsive_thin_endometrium

Reasearchgate.net has provided me with a lot of information about our health and bodies in general, but this article seems like it was written for me to read. Here, a 35 yr-old woman with premature ovarian failure and atrophic/thin endometrium gave birth to a child….and her lining measurement at transfer was a whopping 3.5mm. Yes, I typed that correctly, 3.5mm folks.

Now, most people would say….”Why in the world would they transfer an embryo into a uterus with that measurement in the first place?!?” Well, first of all, where she is from, surrogacy is illegal and second, because of a little test called the ERA Test, Endometrial Receptivity Array.

It can basically tell you if your lining is “pre-receptive”, “receptive”, or “post-receptive”. Some people are having failed IVF’s and FET’s simply due to the fact that they are transferring their embryo on the wrong day. Most people have a 5 day transfer of a 5 day blastocyst, but some people need a 6 day transfer of a 5 day blast, or a 7 day transfer…and some opposite…some need a 4 day transfer, etc. How exciting that they can take a biopsy and it can show if it’s receptive to an embryo or not!? I think this is such a breakthrough and I believe will help a lot of women.

So that brings it back to me. Me and my chronically thin lining. It has plagued me for YEARS. If you’ve followed me for a while, you know this. At one point last year, every single month, I went through the FET process. ALL the pills, shots, meds, ultrasounds, etc…..and every, single time…it was cancelled due to thin lining. Just exhausting.

Now, I’ve known about this ERA test for almost 2 years. I just thought my lining needed to be more at 6mm to really try it. I guess when I read this paper, I missed the 3.5mm! How in the world could I miss that part?

So that’s what I’m going to do. If my lining is at 4mm….I’m still going to do the test. If it surprises me and gets to 6mm or dare I say 7mm, I’ll try it then too.

I mean, at this point, I have nothing to lose. More time? Well, that’s happening as we speak. More money? Well, this is why we work and don’t own a home.

Surrogacy is my next plan…and that “plan” of mine was stopped before it could even begin.

So is this it? Could this be the missing piece of the puzzle to me bringing home my embabies??

In MY very own uterus??

Only time will tell, I currently have a cyst(that’s been hanging around for 2 months! boo) so that needs to disappear and after that I’ll have a 4th hysteroscopy and then try to grow this lining for the biopsy for the ERA. It’s a long process but I’ve got nothing but time….time and faith that all of this will bring me my babies.

My embryos that have been frozen for almost 2 years…..2 years.

I won’t stop…I haven’t forgotten about you babies…I just want to give you a safe home to grow.

So that’s what I’m determined to do…..and it WILL happen…

Some way….some how….it will happen.

Mark my word….I won’t stop until it does. Period.

 

 

 

IVF #3—Stim Days 1-5

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Well, well, well….here we are AGAIN,

Full IVF #3….it’s interesting to me when people count FET cycles as IVF cycles…because if I were to do that, it would be IVF #9 or #10…and that just sounds…overwhelming!! Yikes…so I’ll stick with my calculations….

And this is IVF #3….

So, I know the deal….but I still don’t like it.

The whole reason why we decided to do another IVF is that after 6+ cancelled FET cycles, we needed to do something new. Something different to see if my lining will grow with these stim meds and I am getting older…I’ll be 38 this year…(omg). So my RE is getting concerned about the quality of my eggs and frankly we don’t even know if the embryos we have frozen are viable…and, again, this flipping lining. I mean, it is just an absolute MESS….so here we are.

As some of you read, this cycle started out with a hiccup. My sonohystogram had a little “bump”. Basically it looked like a small polyp or scar tissue or blood clot or something. My RE didn’t seem too concerned but I certainly was. He said if my lining cooperates then there would be no reason why we couldn’t transfer one embryo to see. But obviously, I want to give my babies a really good chance. I’ve never had a transfer and I don’t want to have my first transfer with questions going into it.

So here we go with IVF#3. I also only have one ovary so he’s treating me with a DOR protocol. I did NOT take BC pills before this cycle…only Estrace (IVF#1 I used BC pills and 5 eggs retrieved, IVF#2 I used Estrace and 11 eggs retrieved)

Stim Day 1: 450IU Gonal-F and 150IU Menopur–I had to give myself these shots since the hubby was out of town…booo…but I did it and only minimal bruising…that is a win! btw..I always ice and always take the meds out of the fridge about 1-2 hours before I give myself the shots so they are not cold going into my body…ouch!

Stim Day 2: 450IU Gonal-F and 150IU Menopur-Once again, giving myself the shots…o.k…I’m fine and feel like a pro (I guess I kind of am by now!)

Stim Day 3: 300IU Gonal-F and 150IU Menopur-Hubby is back and gives me the shots. Headaches ensue and bloating begins.

Stim Day 4: Bloodtest to check E2: 422. RE says that is a good number(I think it’s a little high for 3 days of stims??) and I continue on 300IU Gonal-F and 150IU Menopur. I start to get weird under my ribs feeling in my stomach.

Stim Day 5:Weird pressure under ribs feeling so I go to acupuncture (every week for the past 2 years!) to get the blood flowing and see if she can help with the pain in my stomach. Ultrasound: 3-5 eggs seen and lining non-existant with fluid 🙁 I am seriously SO over this. I don’t understand what is wrong with me?? 🙁

So, that is that. My lining SUCKS. Pretty much no matter what I do…it sucks.

I didn’t cry. I didn’t get upset. I just took it..like a champ. I’m going to focus on these eggs. And screw you lining!

So eggs, please grow into my future children. I can’t let the stress of my lining never cooperating to hinder this process. I’m in it now and just have to keep going to retrieval.

So, who knows if I’ll ever be able to transfer. More and more I think that, unfortunately.

I just won’t put my embryos in a place where they are destined to be doomed. A 3-4mm lining with fluid is exactly that. They wouldn’t have a chance.

So I’ll focus on the good.

For some having 3-5 eggs in an IVF cycle would be depressing.

Not being able to transfer during their fresh/frozen cycle would be defeating.

And never being able to transfer after almost 3 years of trying would be devastating.

But this is my life. And I am o.k. and even happy.

I am happy that I live in 2015 where IVF is even possible. I am happy if I even have ONE viable, healthy embryo that becomes my child. I am happy that my husband and I work hard to be able to pay for these treatments and sacrifice not owning a home. And I am happy that I have the faith to be o.k with all of this…the good, the bad and the ugly(lining).

Because I have a focus…and I might not be able to see the finish line….but I know that it is there.

I will focus on that finish line that I cannot see. I know I will have my child at the end of ALL of this. And that is all I will think about. When I think of that…all is good and this mess is just a means to the end. If all of this gets me to my child…every tear, pain, money, stress…will be worth it and I wouldn’t change a thing.

So friends….that’s my game plan. I may not see the finish line but I will keep going, and going and going.

I mean…what am I running…an ultramarathon??? I didn’t sign up for this!

I’ve never even ran a half marathon…but I’m in this and I’ll finish.

Mark my word…I will see that finish line and I WILL FINISH THIS RACE!!!!